ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SOX6

Function : SRY-box 6
Description : This gene encodes a member of the D subfamily of sex determining region y-related transcription factors that are characterized by a conserved DNA-binding domain termed the high mobility group box and by their ability to bind the minor groove of DNA. The encoded protein is a transcriptional activator that is required for normal development of the central nervous system, chondrogenesis and maintenance of cardiac and skeletal muscle cells. The encoded protein interacts with other family members to cooperatively activate gene expression. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Mar 2009]

Classification  

Super Class Other all-alpha-helical DNA-binding domains
Class High-mobility group (HMG) domain factors
Family SOX-related factors
Sub Family Group D

External references

Ensembl ENSG00000110693
RefSeq NP_001139283
Uniprot P35712
Aliases HSSOX6, SOXD
UCSC Gene coordinates chr11:15966448-16476387

External Links

JASPAR MA0515.1
Wikipedia SOX6
WikiGenes SOX6
Transcription Factor Encylopedia SOX6    
GeneCards SOX6
FactorBook SOX6


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SOX6

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SOX6