ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SP1

Function : Sp1 transcription factor
Description : The protein encoded by this gene is a zinc finger transcription factor that binds to GC-rich motifs of many promoters. The encoded protein is involved in many cellular processes, including cell differentiation, cell growth, apoptosis, immune responses, response to DNA damage, and chromatin remodeling. Post-translational modifications such as phosphorylation, acetylation, glycosylation, and proteolytic processing significantly affect the activity of this protein, which can be an activator or a repressor. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2014]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family Three-zinc finger Krüppel-related factors
Sub Family Sp1-like factors

External references

Ensembl ENSG00000185591
RefSeq NP_001238754
Uniprot P08047
Aliases -
UCSC Gene coordinates chr12:53380194-53416445

External Links

JASPAR MA0079.3
Wikipedia SP1
WikiGenes SP1
Transcription Factor Encylopedia SP1    
GeneCards SP1
FactorBook SP1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SP1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SP1