Function : Sp4 transcription factor
Description : The protein encoded by this gene is a transcription factor that can bind to the GC promoter region of a variety of genes, including those of the photoreceptor signal transduction system. The encoded protein binds to the same sites in promoter CpG islands as does the transcription factor SP1, although its expression is much more restricted compared to that of SP1. This gene may be involved in bipolar disorder and schizophrenia. [provided by RefSeq, May 2016]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | Three-zinc finger Krüppel-related factors |
| Sub Family | Sp1-like factors |
| Ensembl | ENSG00000105866 |
| RefSeq | NP_001313471 |
| Uniprot | Q02446 |
| Aliases | HF1B, SPR-1 |
| UCSC Gene coordinates | chr7:21428070-21514760 |
| JASPAR | MA0685.1 |
| Wikipedia | SP4 |
| WikiGenes | SP4 |
| Transcription Factor Encylopedia | SP4 |
| GeneCards | SP4 |
| FactorBook | SP4 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |