ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SPI1

Function : Spi-1 proto-oncogene
Description : This gene encodes an ETS-domain transcription factor that activates gene expression during myeloid and B-lymphoid cell development. The nuclear protein binds to a purine-rich sequence known as the PU-box found near the promoters of target genes, and regulates their expression in coordination with other transcription factors and cofactors. The protein can also regulate alternative splicing of target genes. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Classification  

Super Class Helix-turn-helix domains
Class Tryptophan cluster factors
Family Ets-related factors
Sub Family Spi-like factors

External references

Ensembl ENSG00000066336
RefSeq NP_001074016
Uniprot P17947
Aliases OF, PU.1, SFPI1, SPI-1, SPI-A
UCSC Gene coordinates chr11:47354857-47395639

External Links

JASPAR MA0080.4
Wikipedia SPI1
WikiGenes SPI1
Transcription Factor Encylopedia SPI1
GeneCards SPI1
FactorBook SPI1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SPI1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SPI1