Function : sterol regulatory element binding transcription factor 2
Description : This gene encodes a member of the a ubiquitously expressed transcription factor that controls cholesterol homeostasis by regulating transcription of sterol-regulated genes. The encoded protein contains a basic helix-loop-helix-leucine zipper (bHLH-Zip) domain and binds the sterol regulatory element 1 motif. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]
| Super Class | Basic domains |
| Class | Basic helix-loop-helix factors (bHLH) |
| Family | bHLH-ZIP factors |
| Sub Family | SREBP factors |
| Ensembl | ENSG00000198911 |
| RefSeq | NP_004590 |
| Uniprot | Q12772 |
| Aliases | SREBP-2, SREBP2, bHLHd2 |
| UCSC Gene coordinates | chr22:41833078-41907307 |
| JASPAR | MA0596.1 MA0828.1 |
| Wikipedia | SREBF2 |
| WikiGenes | SREBF2 |
| Transcription Factor Encylopedia | SREBF2 |
| GeneCards | SREBF2 |
| FactorBook | SREBF2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |