ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

SRF

Function : serum response factor
Description : This gene encodes a ubiquitous nuclear protein that stimulates both cell proliferation and differentiation. It is a member of the MADS (MCM1, Agamous, Deficiens, and SRF) box superfamily of transcription factors. This protein binds to the serum response element (SRE) in the promoter region of target genes. This protein regulates the activity of many immediate-early genes, for example c-fos, and thereby participates in cell cycle regulation, apoptosis, cell growth, and cell differentiation. This gene is the downstream target of many pathways; for example, the mitogen-activated protein kinase pathway (MAPK) that acts through the ternary complex factors (TCFs). Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]

Classification  

Super Class alpha-Helices exposed by beta-structures
Class MADS box factors
Family Responders to external signals (SRF/RLM1)
Sub Family None

External references

Ensembl ENSG00000112658
RefSeq NP_001278930
Uniprot P11831
Aliases MCM1
UCSC Gene coordinates chr6:43171294-43181505

External Links

JASPAR MA0083.3
Wikipedia SRF
WikiGenes SRF
Transcription Factor Encylopedia SRF
GeneCards SRF
FactorBook SRF


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for SRF

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for SRF