ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

STAT1

Function : signal transducer and activator of transcription 1
Description : The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Jul 2008]

Classification  

Super Class Immunoglobulin fold
Class STAT domain factors
Family STAT factors
Sub Family None

External references

Ensembl ENSG00000115415
RefSeq NP_009330
Uniprot P42224
Aliases CANDF7, IMD31A, IMD31B, IMD31C, ISGF-3, STAT91
UCSC Gene coordinates chr2:190969035-191014249

External Links

JASPAR MA0137.3
Wikipedia STAT1
WikiGenes STAT1
Transcription Factor Encylopedia STAT1
GeneCards STAT1
FactorBook STAT1


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for STAT1

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for STAT1