Function : transcription factor 7 like 2
Description : This gene encodes a high mobility group (HMG) box-containing transcription factor that plays a key role in the Wnt signaling pathway. The protein has been implicated in blood glucose homeostasis. Genetic variants of this gene are associated with increased risk of type 2 diabetes. Several transcript variants encoding multiple different isoforms have been found for this gene.[provided by RefSeq, Oct 2010]
| Super Class | Other all-alpha-helical DNA-binding domains |
| Class | High-mobility group (HMG) domain factors |
| Family | TCF-7-related factors |
| Sub Family | None |
| Ensembl | ENSG00000148737 |
| RefSeq | NP_001139746 |
| Uniprot | Q9NQB0 |
| Aliases | TCF-4, TCF4 |
| UCSC Gene coordinates | chr10:112950218-113167677 |
| JASPAR | MA0523.1 |
| Wikipedia | TCF7L2 |
| WikiGenes | TCF7L2 |
| Transcription Factor Encylopedia | TCF7L2 |
| GeneCards | TCF7L2 |
| FactorBook | TCF7L2 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |