Function : transcription factor AP-4
Description : Transcription factors of the basic helix-loop-helix-zipper (bHLH-ZIP) family contain a basic domain, which is used for DNA binding, and HLH and ZIP domains, which are used for oligomerization. Transcription factor AP4 activates both viral and cellular genes by binding to the symmetrical DNA sequence CAGCTG (Mermod et al., 1988 [PubMed 2833704]; Hu et al., 1990 [PubMed 2123466]).[supplied by OMIM, Jul 2009]
| Super Class | Basic domains |
| Class | Basic helix-loop-helix factors (bHLH) |
| Family | bHLH-ZIP factors |
| Sub Family | AP-4 |
| Ensembl | ENSG00000090447 |
| RefSeq | NP_003214 |
| Uniprot | Q01664 |
| Aliases | AP-4, bHLHc41 |
| UCSC Gene coordinates | chr16:4257185-4272999 |
| JASPAR | MA0691.1 |
| Wikipedia | TFAP4 |
| WikiGenes | TFAP4 |
| Transcription Factor Encylopedia | TFAP4 |
| GeneCards | TFAP4 |
| FactorBook | TFAP4 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |