Function : DNA topoisomerase I
Description : This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one another, thus altering the topology of DNA. This gene is localized to chromosome 20 and has pseudogenes which reside on chromosomes 1 and 22. [provided by RefSeq, Jul 2008]
| Super Class | Unknown |
| Class | Unknown |
| Family | Unknown |
| Sub Family | Unknown |
| Ensembl | ENSG00000198900 |
| RefSeq | NP_003277 |
| Uniprot | P11387 |
| Aliases | TOPI |
| UCSC Gene coordinates | chr20:41028821-41124486 |
| JASPAR | TOP1 |
| Wikipedia | TOP1 |
| WikiGenes | TOP1 |
| Transcription Factor Encylopedia | TOP1 |
| GeneCards | TOP1 |
| FactorBook | TOP1 |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |