ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

UBTF

Function : upstream binding transcription factor, RNA polymerase I
Description : This gene encodes a member of the HMG-box DNA-binding protein family. The encoded protein plays a critical role in ribosomal RNA transcription as a key component of the pre-initiation complex, mediating the recruitment of RNA polymerase I to rDNA promoter regions. The encoded protein may also play important roles in chromatin remodeling and pre-rRNA processing, and its activity is regulated by both phosphorylation and acetylation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3, 11 and X and the long arm of chromosome 11. [provided by RefSeq, Aug 2011]

Classification  

Super Class Other all-alpha-helical DNA-binding domains
Class High-mobility group (HMG) domain factors
Family UBF-related factors
Sub Family UBF-related factors

External references

Ensembl ENSG00000108312
RefSeq NP_001070151
Uniprot P17480
Aliases CONDBA, NOR-90, UBF, UBF-1, UBF1, UBF2
UCSC Gene coordinates chr17:44205032-44221625

External Links

JASPAR UBTF
Wikipedia UBTF
WikiGenes UBTF
Transcription Factor Encylopedia UBTF    
GeneCards UBTF
FactorBook UBTF


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for UBTF

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for UBTF