Function : zinc finger and BTB domain containing 16
Description : This gene is a member of the Krueppel C2H2-type zinc-finger protein family and encodes a zinc finger transcription factor that contains nine Kruppel-type zinc finger domains at the carboxyl terminus. This protein is located in the nucleus, is involved in cell cycle progression, and interacts with a histone deacetylase. Specific instances of aberrant gene rearrangement at this locus have been associated with acute promyelocytic leukemia (APL). Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
| Super Class | Zinc-coordinating DNA-binding domains |
| Class | C2H2 zinc finger factors |
| Family | More than 3 adjacent zinc finger factors |
| Sub Family | unclassified |
| Ensembl | ENSG00000109906 |
| RefSeq | NP_005997 |
| Uniprot | Q05516 |
| Aliases | PLZF, ZNF145 |
| UCSC Gene coordinates | chr11:114059575-114256764 |
| JASPAR | ZBTB16 |
| Wikipedia | ZBTB16 |
| WikiGenes | ZBTB16 |
| Transcription Factor Encylopedia | ZBTB16 |
| GeneCards | ZBTB16 |
| FactorBook | ZBTB16 |
| Datasets quality |
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DNA constraint | Motifs | |
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UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |
| Datasets quality |
|
|
DNA constraint | Motifs | |
|
UCSC genome browser |
| All peaks | BED file | ![]() |
| Merged peaks (non-redundant peaks) |
BED file | ![]() |
| Peak sequences | FASTA file |