ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

ZBTB33

Function : zinc finger and BTB domain containing 33
Description : This gene encodes a transcriptional regulator with bimodal DNA-binding specificity, which binds to methylated CGCG and also to the non-methylated consensus KAISO-binding site TCCTGCNA. The protein contains an N-terminal POZ/BTB domain and 3 C-terminal zinc finger motifs. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of repressive chromatin structures in target gene promoters. It may contribute to the repression of target genes of the Wnt signaling pathway, and may also activate transcription of a subset of target genes by the recruitment of catenin delta-2 (CTNND2). Its interaction with catenin delta-1 (CTNND1) inhibits binding to both methylated and non-methylated DNA. It also interacts directly with the nuclear import receptor Importin-&

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family Other factors with up to three adjacent zinc fingers
Sub Family Factors with 2-3 adjacent zinc fingersand a BTB/POZ domain

External references

Ensembl ENSG00000177485
RefSeq NP_006768
Uniprot Q86T24
Aliases ZNF-kaiso, ZNF348
UCSC Gene coordinates chrX:120250751-120258395

External Links

JASPAR MA0527.1
Wikipedia ZBTB33
WikiGenes ZBTB33
Transcription Factor Encylopedia ZBTB33    
GeneCards ZBTB33
FactorBook ZBTB33


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for ZBTB33

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for ZBTB33