ZEB1
Function : zinc finger E-box binding homeobox 1
Description : This gene encodes a zinc finger transcription factor. The encoded protein likely plays a role in transcriptional repression of interleukin 2. Mutations in this gene have been associated with posterior polymorphous corneal dystrophy-3 and late-onset Fuchs endothelial corneal dystrophy. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Mar 2010]
Classification 
| Super Class | Helix-turn-helix domains |
| Class | Homeo domain factors |
| Family | HD-ZF factors |
| Sub Family | ZEB |
External references
| Ensembl | ENSG00000148516 |
| RefSeq | NP_001310578 |
| Uniprot | P37275 |
| Aliases | AREB6, BZP, DELTAEF1, FECD6, NIL2A, PPCD3, TCF8, ZFHEP, ZFHX1A |
| UCSC Gene coordinates | chr10:31318494-31529813 |
External Links
| JASPAR | MA0103.3 |
| Wikipedia | ZEB1 |
| WikiGenes | ZEB1 |
| Transcription Factor Encylopedia | ZEB1 |
| GeneCards | ZEB1 |
| FactorBook | ZEB1 |
