ZEB2
Function : zinc finger E-box binding homeobox 2
Description : The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]
Classification 
| Super Class | Helix-turn-helix domains |
| Class | Homeo domain factors |
| Family | HD-ZF factors |
| Sub Family | ZEB |
External references
| Ensembl | ENSG00000169554 |
| RefSeq | NP_055610 |
| Uniprot | O60315 |
| Aliases | HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B |
| UCSC Gene coordinates | chr2:144384374-144520390 |
External Links
| JASPAR | ZEB2 |
| Wikipedia | ZEB2 |
| WikiGenes | ZEB2 |
| Transcription Factor Encylopedia | ZEB2 |
| GeneCards | ZEB2 |
| FactorBook | ZEB2 |
