ReMap 2018 v1.2

An integrative ChIP-seq analysis of regulatory regions

ZNF384

Function : zinc finger protein 384
Description : This gene encodes a C2H2-type zinc finger protein, which may function as a transcription factor. This gene also contains long CAG trinucleotide repeats that encode consecutive glutamine residues. The protein appears to bind and regulate the promoters of the extracellular matrix genes MMP1, MMP3, MMP7 and COL1A1. Studies in mouse suggest that nuclear matrix transcription factors (NP/NMP4) may be part of a general mechanical pathway that couples cell construction and function during extracellular matrix remodeling. Alternative splicing results in multiple transcript variants. Recurrent rearrangements of this gene with the Ewing's sarcoma gene, EWSR1 on chromosome 22, or with the TAF15 gene on chromosome 17, or with the TCF3 (E2A) gene on chromosome 19, have been observed in acute leukemia. A related pseudogene has been identified on chromosome 7. [provided by RefSeq, Apr 2011]

Classification  

Super Class Zinc-coordinating DNA-binding domains
Class C2H2 zinc finger factors
Family More than 3 adjacent zinc finger factors
Sub Family ZNF362-like factors

External references

Ensembl ENSG00000126746
RefSeq NP_597733
Uniprot Q8TF68
Aliases CAGH1, CAGH1A, CIZ, ERDA2, NMP4, NP, TNRC1
UCSC Gene coordinates chr12:6666476-6689571

External Links

JASPAR MA1125.1
Wikipedia ZNF384
WikiGenes ZNF384
Transcription Factor Encylopedia ZNF384    
GeneCards ZNF384
FactorBook ZNF384


Genomic visualization & Analyses for MACS

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for MACS

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

MACS - Datasets retained for ZNF384

Genomic visualization & Analyses for JAMM

Datasets
quality
DNA constraint
Motifs UCSC genome
browser

Downloading peaks and sequences for JAMM

All peaks BED file
Merged peaks
(non-redundant peaks)
BED file
Peak sequences FASTA file

JAMM - Datasets retained for ZNF384